![]() ![]() ![]() Opana was linked to the 2015 HIV outbreak in the rural Indiana community of Austin that resulted in dozens of confirmed HIV cases in a town of only around 4,000 people. “This action will protect the public from further potential for misuse and abuse of this product.” “When we determined that the product had dangerous unintended consequences, we made a decision to request its withdrawal from the market,” said Janet Woodcock, M.D., director of the FDA’s Center for Drug Evaluation and Research in a statement. The FDA was able to link the shift from Opana inhalation to injection with a serious outbreak of HIV and hepatitis C, as well as cases of thrombotic microangiopathy, a dangerous blood disorder. As a result, some who abuse Opana ER are injecting the drug more frequently. It has a short half-life, meaning the desired high is gone sooner than with other opioids. Oxymorphone hydrochloride is known for the potent high that results when it is ground, mixed with water, and injected. The Food and Drug Administration has asked Endo Pharmaceuticals, the manufacturer of Opana ER, an extended-release semi-synthetic opioid painkiller, to remove the drug from the market, after the agency concluded that the drug’s potential for abuse outweighed its therapeutic value.Įndo had reformulated Opana ER (oxymorphone hydrochloride) to make it more difficult to abuse, but the FDA determined that this change ultimately resulted in a “significant shift in the route of abuse of Opana ER from nasal to injection.” ![]() 6.8.17 6:28 PM EDT By Meg Marco opana connection opana endo pharmaceuticals fda drugs opioids opioid abuse ![]()
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